Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 16/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631308 | 0.79 | HCAR2 (0.63) | HCAR2DAO | |
| SCHEMBL9213204 | 0.77 | KDM4C (0.56) | HCAR2TSHR | |
| SCHEMBL12263262 | 0.76 | HCAR2 (0.55) | HCAR2DAOKMT2ATSHR | |
| SCHEMBL31741716 | 0.76 | HCAR2 (0.59) | HCAR2DAOKMT2ATSHR | |
| SCHEMBL15859525 | 0.76 | HCAR2 (0.55) | HCAR2DAOKMT2ATSHR | |
| SCHEMBL17065994 | 0.76 | HCAR2 (0.55) | HCAR2DAOKMT2ATSHR | |
| SCHEMBL4877467 | 0.74 | HCAR2 (0.53) | HCAR2DAOKMT2ATSHR | |
| SCHEMBL29956356 | 0.74 | HCAR2 (0.53) | HCAR2DAOKMT2ATSHR | |
| SCHEMBL10862602 | 0.74 | KDM4E (0.51) | HCAR2KMT2A | |
| SCHEMBL29240564 | 0.73 | HCAR2 (0.41) | HCAR2DAOKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6600071-B2 | Starting materials or intermediates and the cyclization of these under suitable reaction conditions to give compounds of the formula I. The intermediates of the formula II are novel. for argrochemicals | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |