Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.64 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238579 | 0.93 | FFAR1 (0.65) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7234584 | 0.81 | CYSLTR1 (0.60) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL1419872 | 0.80 | FFAR1 (0.77) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10446852 | 0.80 | CYSLTR1 (0.75) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10446560 | 0.80 | CYSLTR1 (0.79) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10544473 | 0.78 | CYSLTR1 (0.84) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7718896 | 0.78 | GPBAR1 (0.90) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7457682 | 0.78 | GPBAR1 (0.90) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6088569 | 0.78 | FFAR1 (0.73) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9045246 | 0.78 | GPBAR1 (0.80) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035136-A1 | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBVIE INC. | 2002-03-21 | — | — | US | claimed |
| WO-2002018321-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | claimed |
| US-6627767-B2 | Controlling cellular metabolism | ABBOTT LABORATORIES | 2003-09-30 | — | — | US | disclosed |
| US-20020035136-A1 | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBVIE INC. | 2002-03-21 | — | — | US | disclosed |
| WO-2002018321-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035136-A1 | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors | PPM1A, PPM1F, PPM1G | FFAR1 481/4885AKR1B1 516/4885CYSLTR1 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.