Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 14/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965014 | 0.83 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2ALOX5HDAC6FFAR1 | |
| SCHEMBL7234745 | 0.81 | FFAR1 (0.64) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL9584140 | 0.78 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2ALOX5HDAC6FFAR1 | |
| SCHEMBL7238579 | 0.78 | FFAR1 (0.65) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL2108349 | 0.76 | ALOX5 (0.61) | CYSLTR1CYSLTR2ALOX5HDAC6FFAR1 | |
| Bicarbonate SCHEMBL9374712 | 0.76 | CYSLTR1 (0.72) | CYSLTR1CYSLTR2ALOX5HDAC6FFAR1 | |
| SCHEMBL9135133 | 0.75 | GPBAR1 (0.66) | CYSLTR1CYSLTR2ALOX5HDAC6FFAR1 | |
| SCHEMBL9474669 | 0.75 | ALOX5 (0.64) | CYSLTR1CYSLTR2ALOX5HDAC6FFAR1 | |
| SCHEMBL9137854 | 0.75 | GPBAR1 (0.66) | CYSLTR1CYSLTR2ALOX5HDAC6FFAR1 | |
| SCHEMBL8965425 | 0.74 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2ALOX5HDAC6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035136-A1 | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBVIE INC. | 2002-03-21 | — | — | US | claimed |
| WO-2002018321-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | claimed |
| US-6627767-B2 | Controlling cellular metabolism | ABBOTT LABORATORIES | 2003-09-30 | — | — | US | disclosed |
| US-20020035136-A1 | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBVIE INC. | 2002-03-21 | — | — | US | disclosed |
| WO-2002018321-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035136-A1 | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors | PPM1A, PPM1F, PPM1G | CYSLTR1 4092/4885CYSLTR2 4645/4885ALOX5 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.