Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235114 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HTTTSHRKMT2AMAPT | |
| SCHEMBL14399301 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HTTTSHRKMT2AMAPT | |
| SCHEMBL1844679 | 0.78 | KDM4E (0.38) | ALDH1A1TSHRKMT2AMAPTPKM | |
| SCHEMBL1844680 | 0.78 | KDM4E (0.38) | ALDH1A1TSHRKMT2AMAPTPKM | |
| SCHEMBL4181616 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HTTTSHRKMT2AMAPT | |
| SCHEMBL1939079 | 0.73 | NPC1 (0.48) | ALDH1A1HTTTSHRKMT2AMAPT | |
| SCHEMBL1939080 | 0.73 | NPC1 (0.48) | ALDH1A1HTTTSHRKMT2AMAPT | |
| SCHEMBL1531393 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HTTTSHRKMT2AMAPT | |
| SCHEMBL1531396 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HTTTSHRKMT2AMAPT | |
| SCHEMBL5251556 | 0.70 | LMNA (0.56) | ALDH1A1HTTTSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541630-B1 | 7-bromo-3-methyl-3,4- dihydrothieno(3,2-d)pyrimidin-4-one | AGREVO UK LIMITED (GB) | 2003-04-01 | — | — | US | disclosed |
| EP-0982992-B1 | Use of thienopyrimidines as fungicides | AVENTIS CROPSCIENCE UK LTD (GB) | 2002-09-25 | — | — | EP | disclosed |
| US-6432964-B1 | A THIENYLPYRIMIDINE COMPOUND | AGREVO UK LIMITED (GB) | 2002-08-13 | — | — | US | disclosed |
| EP-0982992-A1 | FUNGICIDES | AgrEvo UK Limited (GB) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998049899-A1 | FUNGICIDES | AGREVO UK LIMITED (GB) | 1998-11-12 | — | — | WO | disclosed |