SCHEMBL7235196

SCHEMBL7235196

COC(=O)[C@H]1CCCN(C(=O)c2ccccc2)C1

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
POLB P06746 2/20 0.60
HPGD P15428 3/20 0.56
LMNA P02545 1/20 0.56
HIF1A Q16665 1/20 0.56
GRM3 Q14832 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54
PKM P14618 1/20 0.54
HTT P42858 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7235193 1.00 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2POLBHPGDLMNA
Hydrochloric Acid SCHEMBL10556596 0.85 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2POLBHPGDLMNA
SCHEMBL1223375 0.85 HPGD (0.76) ALDH1A1SMN1; SMN2POLBHPGDHTT
SCHEMBL19209096 0.85 PDK2 (0.54) ALDH1A1HPGD
SCHEMBL28763663 0.84 HPGD (0.61) ALDH1A1SMN1; SMN2POLBHPGDGRM3
SCHEMBL13804124 0.84 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2POLBHPGDLMNA
SCHEMBL16442058 0.84 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2POLBHPGDGRM3
SCHEMBL1520334 0.84 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2POLBHPGDGRM3
SCHEMBL7232912 0.84 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2POLBHPGDGRM3
SCHEMBL12060563 0.83 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2POLBHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664271-B1 Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae ELI LILLY AND COMPANY 2003-12-16 US claimed
US-6664271-B1 Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae ELI LILLY AND COMPANY 2003-12-16 US disclosed
WO-2000071519-A2 IMMUNOPOTENTIATOR AGENTS ELI LILLY AND COMPANY (US) 2000-11-30 WO disclosed