Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232184 | 0.81 | KMT2A (0.76) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7242700 | 0.77 | HSD17B10 (0.69) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7234671 | 0.75 | KMT2A (0.60) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7233792 | 0.75 | HSD17B10 (0.65) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL15322838 | 0.73 | MAPT (0.45) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7241560 | 0.73 | ALDH1A1 (0.56) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7233937 | 0.71 | ALDH1A1 (0.70) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL19961339 | 0.71 | ALDH1A1 (0.67) | HSD17B10MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7234226 | 0.70 | MEN1 (0.57) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28630788 | 0.69 | ALDH1A1 (0.55) | HSD17B10MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | claimed |
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | disclosed |