Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.46 |
| ▸ | TPH1 | P17752 | 9/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228315 | 0.86 | GRM2 (0.51) | GRM2ITGB3ITGA2B | |
| SCHEMBL7229931 | 0.85 | GRM2 (0.49) | GRM2 | |
| SCHEMBL7240907 | 0.84 | ITGB3 (0.51) | GRM2ITGB3ITGA2B | |
| SCHEMBL7240309 | 0.80 | ITGB3 (0.44) | GRM2ITGB3ITGA2B | |
| SCHEMBL7235962 | 0.80 | GRM2 (0.43) | GRM2 | |
| SCHEMBL7237956 | 0.79 | GRM2 (0.41) | GRM2 | |
| SCHEMBL3267490 | 0.78 | GRM2 (0.53) | GRM2ITGB3ITGA2B | |
| SCHEMBL8146492 | 0.74 | GRM2 (0.54) | GRM2ITGB3ITGA2B | |
| SCHEMBL7239759 | 0.73 | ITGB3 (0.56) | GRM2ITGB3ITGA2B | |
| SCHEMBL7228484 | 0.72 | GRM2 (0.41) | GRM2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602876-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6204280-B1 | OXAZOLIDINONE DERIVATIVE, ANTICOAGULANT | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 2001-03-20 | — | — | US | disclosed |