Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.54 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750534 | 1.00 | CLK1 (0.54) | CLK1CSNK1DCSNK1EDYRK1ANPC1 | |
| Isoquinoline SCHEMBL7993276 | 0.95 | CLK1 (0.50) | CLK1CSNK1DCSNK1EDYRK1ANPC1 | |
| Quinoline SCHEMBL7992158 | 0.93 | ALDH1A1 (0.57) | CLK1CSNK1DCSNK1EDYRK1ANPC1 | |
| SCHEMBL50867 | 0.83 | ALDH1A1 (0.61) | DYRK1ANPC1RAB9APOLBPDGFRB | |
| SCHEMBL29726025 | 0.83 | ALDH1A1 (0.61) | DYRK1ANPC1RAB9APOLBPDGFRB | |
| SCHEMBL31733917 | 0.81 | ALDH1A1 (0.58) | DYRK1ANPC1RAB9APOLBPDGFRB | |
| SCHEMBL29471812 | 0.81 | ALDH1A1 (0.58) | DYRK1ANPC1RAB9APOLBPDGFRB | |
| Ammonia Solution, Strong SCHEMBL29036762 | 0.81 | ALDH1A1 (0.58) | DYRK1ANPC1RAB9APOLBPDGFRB | |
| SCHEMBL29845770 | 0.81 | ALDH1A1 (0.58) | DYRK1ANPC1RAB9APOLBPDGFRB | |
| SCHEMBL30422685 | 0.81 | ALDH1A1 (0.58) | DYRK1ANPC1RAB9APOLBPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624933-A | Process for the preparation of a 6-fluoro-2-halo-quinoline | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | claimed |
| JP-2300171-A | — | — | None | — | — | JP | disclosed |
| JP-3056464-A | — | — | None | — | — | JP | disclosed |
| US-20250073225-A1 | BIFUNCTIONAL COMPOSITIONS FOR THE TREATMENT OF CANCER | ARMACEUTICA INC (US) | 2025-03-06 | — | — | US | disclosed |
| US-12201626-B2 | Bifunctional compositions for the treatment of cancer | Armaceutica, Inc. (US) | 2025-01-21 | — | — | US | disclosed |
| EP-3793544-B1 | BIFUNCTIONAL COMPOSITIONS FOR THE TREATMENT OF CANCER | ARMACEUTICA INC (US) | 2023-09-20 | — | — | EP | disclosed |
| US-20210361643-A1 | BIFUNCTIONAL COMPOSITIONS FOR THE TREATMENT OF CANCER | ARMACEUTICA INC (US) | 2021-11-25 | — | — | US | disclosed |
| CN-112672741-A | Bifunctional compositions for treating cancer | 阿玛切蒂卡有限公司 | 2021-04-16 | — | — | CN | disclosed |
| EP-3793544-A1 | BIFUNCTIONAL COMPOSITIONS FOR THE TREATMENT OF CANCER | Armaceutica, Inc (US) | 2021-03-24 | — | — | EP | disclosed |
| US-10862046-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-12-08 | — | — | US | disclosed |
| EP-0379412-B1 | 1,8-Benzonaphthyridine derivatives, their preparation and compositions containing them | BELLON LABOR SA ROGER (FR) | 1993-12-01 | — | — | EP | disclosed |
| EP-0536035-A1 | 1,8-Benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1993-04-07 | — | — | EP | disclosed |
| US-5091535-A | ORGANIC PHOTOCHROMIC COMPOUND, A DIMER OF PYRIDO QUINOLINE | SEIKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0431991-A1 | 1,8-Benzonaphthyridine derivatives, their preparation and compositions containing them | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1991-06-12 | — | — | EP | disclosed |
| JP-H0356464-A | 3-PYRIDYL-2-(3-METHYL PYRIDYL)METHANE AND PRODUCTION THEREOF | SEKISUI CHEM CO LTD | 1991-03-12 | — | — | JP | disclosed |
| JP-H02300171-A | 3-PYRIDYL-2-(3-METHYLPYRIDYL)METHANOL AND PREPARATION THEREOF | SEKISUI CHEM CO LTD | 1990-12-12 | — | — | JP | disclosed |
| EP-0394846-A2 | Organic photochromic compound | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-10-31 | — | — | EP | disclosed |
| EP-0379414-A1 | 1,8-Benzonaphthyridine derivatives and their preparation | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1990-07-25 | — | — | EP | disclosed |
| EP-0379412-A1 | 1,8-Benzonaphthyridine derivatives, their preparation and compositions containing them | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1990-07-25 | — | — | EP | disclosed |
| EP-0379413-A1 | 1,8-Benzonaphthyridine derivatives, their production and compositions containing them | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1990-07-25 | — | — | EP | disclosed |