SCHEMBL7235960

SCHEMBL7235960

C=CCOC(=O)Nc1nc(NC(=O)OCC=C)nc(NC(=O)OCC=C)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CSNK2A2 P19784 1/20 0.43
CSNK2A1 P68400 1/20 0.43
MAPT P10636 1/20 0.42
CACNA1B Q00975 1/20 0.42
APBA1 Q02410 1/20 0.42
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40
TUBA1A Q71U36 1/20 0.40
TUBA1C Q9BQE3 1/20 0.40
TUBB6 Q9BUF5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11794737 0.85 ALDH1A1 (0.47) MEN1KMT2ACSNK2A2CSNK2A1MAPT
SCHEMBL10616869 0.81 KMT2A (0.41) MEN1KMT2ACSNK2A2CSNK2A1MAPT
SCHEMBL10616803 0.80 HDAC1 (0.37) MEN1KMT2ACSNK2A2CSNK2A1MAPT
Hydrochloric Acid SCHEMBL10621207 0.79 HDAC1 (0.36) MEN1KMT2ACSNK2A2CSNK2A1MAPT
SCHEMBL1080415 0.79 MEN1 (0.40) MEN1KMT2ACSNK2A2CSNK2A1MAPT
SCHEMBL729016 0.78 MAPT (0.50) MEN1KMT2ACSNK2A2CSNK2A1MAPT
SCHEMBL11645205 0.76 NPC1 (0.55) MEN1KMT2AMAPTALDH1A1TSHR
SCHEMBL5694140 0.74 MEN1 (0.45) MEN1KMT2ACSNK2A2CSNK2A1TUBB4A
SCHEMBL20935228 0.73 CHRNB2 (0.49) MEN1KMT2ACSNK2A2CSNK2A1TUBB4A
SCHEMBL19035598 0.73 CHRNB2 (0.61) MEN1KMT2AMAPTCYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6506898-B1 Halogen-free, purity; curing agents CYTEC TECHNOLOGY CORP. 2003-01-14 US disclosed
EP-0624577-B1 Process for the preparation of 1,3,5-triazine carbamates, at least biscarbamate functional 1,3,5-triazines CYTEC TECH CORP (US) 2001-09-19 EP disclosed
US-6288226-B1 CURING CARBONATES CYTEC TECHNOLOGY CORPORATION 2001-09-11 US disclosed
US-6063922-A Carbamate functional 1,3,5-triazines CYTEC TECHNOLOGY CORP. (US) 2000-05-16 US disclosed
EP-0976739-A2 A Process for the preparation of 1,3,5-triazine carbamates, at least biscarbimate functional 1,3,5-triazines as well as use of 1,3,5-triazine carbamates CYTEC TECHNOLOGY CORP. (US) 2000-02-02 EP disclosed
US-5792866-A Process for the preparation of 1,3,5-triazine carbamates from amino 1,3,5-triazines and organic carbonates CYTEC TECHNOLOGY CORPORATION (US) 1998-08-11 US disclosed
US-5705641-A Process for the preparation of 1,3,5-triazine carbamates from amino-1,3,5-triazines and organic carbonates CYTEC TECHNOLOGY CORP. (US) 1998-01-06 US disclosed
EP-0624577-A1 Process for the preparation of 1,3,5-triazine carbamates, at least biscarbamate functional 1,3,5-triazines and their use as crosslinkers CYTEC TECHNOLOGY CORP. (US) 1994-11-17 EP disclosed