SCHEMBL7236253

SCHEMBL7236253

Cc1ccccc1CN1CCc2ccc(C(=O)CCCC3CCN(Cc4ccccc4N)CC3)cc2CC1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.54
ACHE P22303 15/20 0.51
MCHR1 Q99705 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7235726 0.99 FAAH (0.53) FAAHACHEMCHR1
SCHEMBL7226780 0.94 FAAH (0.59) FAAHACHEMCHR1
Hydrochloric Acid SCHEMBL7236249 0.94 FAAH (0.58) FAAHACHEMCHR1
SCHEMBL7234946 0.89 ACHE (0.60) FAAHACHEMCHR1
Hydrochloric Acid SCHEMBL7227488 0.89 ACHE (0.62) FAAHACHE
SCHEMBL7227784 0.89 ACHE (0.60) FAAHACHE
Hydrochloric Acid SCHEMBL7227310 0.89 ACHE (0.62) FAAHACHE
Hydrochloric Acid SCHEMBL7236440 0.89 FAAH (0.51) FAAHACHEMCHR1
SCHEMBL7235616 0.89 FAAH (0.53) FAAHACHEMCHR1
Hydrochloric Acid SCHEMBL7236011 0.89 ACHE (0.59) FAAHACHEMCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534496-B1 Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2003-03-18 US disclosed