Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225755 | 0.88 | KDM4E (0.45) | CTSAKDM4EL3MBTL1MAPK1NPC1 | |
| SCHEMBL1759891 | 0.84 | KDM4E (0.66) | CTSAKDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL29375401 | 0.84 | KDM4E (0.66) | CTSAKDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL73021 | 0.84 | KDM4E (0.47) | CTSAKDM4EL3MBTL1MAPK1RAB9A | |
| SCHEMBL1615811 | 0.84 | NPC1 (0.46) | KDM4EL3MBTL1MAPK1SMN1; SMN2NPC1 | |
| SCHEMBL2811357 | 0.83 | CYP1A2 (0.44) | CTSAKDM4EL3MBTL1MAPK1MRGPRX4 | |
| SCHEMBL31620653 | 0.83 | GRM5 (0.49) | CTSAMAPK1MRGPRX4SMN1; SMN2CYP1A2 | |
| SCHEMBL16742565 | 0.82 | MRGPRX4 (0.44) | CTSAMAPK1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL7225758 | 0.82 | KDM4E (0.64) | CTSAKDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL17144343 | 0.81 | NOTUM (0.46) | MAPK1MRGPRX4NOTUMGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610853-B1 | N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide | KUREHA KAGAKU KOGYO K.K. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1069112-A1 | N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-01-17 | — | — | EP | disclosed |