Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723633 | 1.00 | TAAR1 (0.69) | TAAR1SMN1; SMN2CA2CA1G6PC1 | |
| SCHEMBL10623357 | 1.00 | TAAR1 (0.69) | TAAR1SMN1; SMN2CA2CA1G6PC1 | |
| SCHEMBL77618 | 0.86 | SMN1; SMN2 (0.67) | TAAR1SMN1; SMN2CA2CA1G6PC1 | |
| SCHEMBL77617 | 0.86 | SMN1; SMN2 (0.67) | TAAR1SMN1; SMN2CA2CA1G6PC1 | |
| SCHEMBL715116 | 0.86 | SMN1; SMN2 (0.67) | TAAR1SMN1; SMN2CA2CA1G6PC1 | |
| SCHEMBL3050606 | 0.84 | SMN1; SMN2 (0.65) | TAAR1SMN1; SMN2CA2CA1G6PC1 | |
| SCHEMBL8543783 | 0.82 | SMN1; SMN2 (0.54) | TAAR1SMN1; SMN2CA2CA1MAPT | |
| SCHEMBL15551980 | 0.81 | CA2 (0.68) | TAAR1SMN1; SMN2CA2CA1G6PC1 | |
| SCHEMBL11586020 | 0.81 | CA2 (0.68) | TAAR1SMN1; SMN2CA2CA1G6PC1 | |
| SCHEMBL8543158 | 0.81 | G6PC1 (0.57) | TAAR1SMN1; SMN2CA2CA1G6PC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027548-A1 | COMPOUNDS AND METHODS FOR PREVENTION AND TREATMENT OF ALZHEIMER'S AND OTHER DISEASES | THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (US) | 2012-03-01 | — | — | WO | disclosed |
| US-8039580-B2 | Dendritic polymers having monophosphonic terminations, method for preparing them, and their use | RHODIA UK LTD. (GB) | 2011-10-18 | — | — | US | disclosed |
| US-4214094-A | ANTILIPEMIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-22 | — | — | US | disclosed |