Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.63 |
| ▸ | CES1 | P23141 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TERT | O14746 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072795 | 1.00 | FAAH (0.63) | FAAHCES1CYP1A2CYP2C19KMT2A | |
| SCHEMBL6120075 | 0.89 | FAAH (0.55) | FAAHCES1CYP1A2KMT2AMEN1 | |
| SCHEMBL28986780 | 0.89 | FAAH (0.55) | FAAHCES1CYP1A2KMT2AMEN1 | |
| SCHEMBL969166 | 0.89 | FAAH (0.55) | FAAHCES1CYP1A2KMT2AMEN1 | |
| SCHEMBL3773103 | 0.86 | FAAH (0.67) | FAAHCES1CYP1A2CYP2C19KMT2A | |
| SCHEMBL4655426 | 0.86 | FAAH (0.67) | FAAHCES1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3776625 | 0.86 | FAAH (0.67) | FAAHCES1CYP1A2CYP2C19KMT2A | |
| SCHEMBL4655425 | 0.86 | FAAH (0.67) | FAAHCES1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9354962 | 0.85 | FAAH (0.65) | FAAHCES1CYP1A2CYP2C19KMT2A | |
| SCHEMBL8935063 | 0.85 | FAAH (0.65) | FAAHCES1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400622-A1 | GENETICALLY ENCODED VOLTAGE INDICATORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-12-05 | — | — | US | disclosed |
| EP-4405375-A1 | GENETICALLY ENCODED VOLTAGE INDICATORS AND USES THEREOF | President and Fellows of Harvard College (US) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023049826-A1 | GENETICALLY ENCODED VOLTAGE INDICATORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-03-30 | — | — | WO | disclosed |
| US-10800829-B2 | Optogenetic probes for measuring membrane potential | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-10-13 | — | — | US | disclosed |
| US-20200123218-A1 | OPTOGENETIC PROBES FOR MEASURING MEMBRANE POTENTIAL | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-04-23 | — | — | US | disclosed |
| EP-3158338-B1 | OPTOGENETIC PROBES FOR MEASURING MEMBRANE POTENTIAL | HARVARD COLLEGE (US) | 2020-03-11 | — | — | EP | disclosed |
| US-10457715-B2 | Optogenetic probes for measuring membrane potential | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-10-29 | — | — | US | disclosed |
| US-10352945-B2 | Optogenetic probes for measuring membrane potential | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-07-16 | — | — | US | disclosed |
| US-10161937-B2 | Systems, methods, and workflows for optogenetics analysis | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-12-25 | — | — | US | disclosed |
| US-20180031572-A1 | OPTOGENETIC PROBES FOR MEASURING MEMBRANE POTENTIAL | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-02-01 | — | — | US | disclosed |
| EP-2609425-A1 | OPTOGENETIC PROBES FOR MEASURING MEMBRANE POTENTIAL | President and Fellows of Harvard College (US) | 2013-07-03 | — | — | EP | disclosed |
| EP-2229948-B1 | Mesenchymal CD34- stem cells for use in diabetes gene therapy | APCETH GMBH & CO KG (DE) | 2012-12-19 | — | — | EP | disclosed |
| WO-2012027358-A1 | OPTOGENETIC PROBES FOR MEASURING MEMBRANE POTENTIAL | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-01 | — | — | WO | disclosed |
| US-20110268714-A1 | CD34 Stem Cell-Related Methods and Compositions | APCETH GMBH & CO. KG | 2011-11-03 | — | — | US | disclosed |
| US-7998472-B2 | CD34 stem cell-related methods and compositions | APCETH GMBH & CO. KG (DE) | 2011-08-16 | — | — | US | disclosed |
| EP-2229948-A1 | Mesenchymal CD34- stem cells for use in diabetes gene therapy | Apceth GmbH & Co. KG (DE) | 2010-09-22 | — | — | EP | disclosed |
| EP-2223696-A1 | Mesenchymal CD34- stem cells for use in wound healing gene therapy | Apceth GmbH & Co. KG (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2162534-A1 | CD34 STEM CELL-RELATED METHODS AND COMPOSITIONS | Apceth GmbH & Co. KG (DE) | 2010-03-17 | — | — | EP | disclosed |
| US-20090041735-A1 | CD34 Stem cell-related methods and compositions | APCETH GMBH & CO. KG (DE) | 2009-02-12 | — | — | US | disclosed |
| WO-2008150368-A1 | CD34 STEM CELL-RELATED METHODS AND COMPOSITIONS | APCETH GMBH & CO. KG (DE) | 2008-12-11 | — | — | WO | disclosed |