Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.67 |
| ▸ | CES1 | P23141 | 2/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | TERT | O14746 | 3/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.59 |
| ▸ | PPARD | Q03181 | 3/20 | 0.59 |
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | FABP4 | P15090 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3776625 | 1.00 | FAAH (0.67) | FAAHCES1HRH3TERTPTPN1 | |
| SCHEMBL8016101 | 0.91 | FAAH (0.56) | FAAHCES1HRH3TERTPTPN1 | |
| SCHEMBL4655425 | 0.89 | FAAH (0.67) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL4655426 | 0.89 | FAAH (0.67) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL3778978 | 0.89 | FAAH (0.59) | FAAHCES1PTPN1PPARGPPARD | |
| SCHEMBL3777756 | 0.89 | FAAH (0.59) | FAAHCES1PTPN1PPARGPPARD | |
| SCHEMBL9435633 | 0.89 | FAAH (0.59) | FAAHCES1PTPN1PPARGPPARD | |
| SCHEMBL3787603 | 0.89 | FAAH (0.59) | FAAHCES1PTPN1PPARGPPARD | |
| SCHEMBL3777162 | 0.89 | FAAH (0.59) | FAAHCES1PTPN1PPARGPPARD | |
| SCHEMBL20497217 | 0.88 | FAAH (0.65) | FAAHCES1HRH3TERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080089932-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. | 2008-04-17 | — | — | US | claimed |
| US-20160151282-A1 | AMPHOTERIC LIPOSOME FORMULATIONS | MARINA BIOTECH INC (US) | 2016-06-02 | — | — | US | disclosed |
| US-9283186-B2 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20140178462-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | MARINA BIOTECH, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| EP-2462924-A2 | Improvements in or relating to amphoteric liposomes. | Marina Biotech, Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120135065-A1 | Amphoteric Liposomes, A Method Of Formulating An Amphoteric Liposome And A Method Of Loading An Amphoteric Liposome | MARINA BIOTECH, INC. | 2012-05-31 | — | — | US | disclosed |
| US-20100330154-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | MARINA BIOTECH, INC. | 2010-12-30 | — | — | US | disclosed |
| EP-2094238-A2 | IMPROVEMENTS IN OR RELATING TO AMPHOTERIC LIPOSOMES | Novosom AG (DE) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008043575-A2 | IMPROVEMENTS IN OR RELATING TO AMPHOTERIC LIPOSOMES | NOVOSOM AG (DE) | 2008-04-17 | — | — | WO | disclosed |
| US-20080089932-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. | 2008-04-17 | — | — | US | disclosed |
| US-20080088046-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | NOVOSOM AG (DE) | 2008-04-17 | — | — | US | disclosed |
| EP-1911443-A1 | Amphoteric liposomes, method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | Novosom AG (DE) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135065-A1 | Amphoteric Liposomes, A Method Of Formulating An Amphoteric Liposome And A Method Of Loading An Amphoteric Liposome | LIPA, SGMS1, SGMS2 | FAAH 248/4885CES1 894/4885HRH3 1082/4885 |
| US-20100330154-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | LIPA, CETP, SGMS1 | FAAH 1830/4885CES1 544/4885HRH3 820/4885 |
| US-20160151282-A1 | AMPHOTERIC LIPOSOME FORMULATIONS | LIPA, SGMS1, SGMS2 | FAAH 241/4885CES1 867/4885HRH3 1030/4885 |
| US-20140178462-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | LIPA, CETP, SGMS1 | FAAH 1830/4885CES1 544/4885HRH3 820/4885 |
| US-20080089932-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | LIPA, SGMS1, SGMS2 | FAAH 248/4885CES1 894/4885HRH3 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.