Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965011 | 0.87 | ALOX5 (0.70) | ALOX5HDAC6 | |
| SCHEMBL8801530 | 0.84 | ALOX5 (0.66) | ALOX5HDAC6 | |
| SCHEMBL9123415 | 0.83 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL7818344 | 0.83 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL9123409 | 0.83 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL9030094 | 0.83 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL7818529 | 0.83 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL2109295 | 0.83 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL2110833 | 0.83 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL9122076 | 0.83 | ALOX5 (1.00) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035136-A1 | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBVIE INC. | 2002-03-21 | — | — | US | claimed |
| WO-2002018321-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | claimed |
| US-6627767-B2 | Controlling cellular metabolism | ABBOTT LABORATORIES | 2003-09-30 | — | — | US | disclosed |
| US-20020035136-A1 | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBVIE INC. | 2002-03-21 | — | — | US | disclosed |
| WO-2002018321-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035136-A1 | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors | PPM1A, PPM1F, PPM1G | ALOX5 2810/4885HDAC6 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.