Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2110833 | 1.00 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL9122076 | 1.00 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL9123409 | 1.00 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL7818529 | 1.00 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL9123415 | 1.00 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL2109295 | 1.00 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL9030094 | 1.00 | ALOX5 (1.00) | ALOX5HDAC6 | |
| Veliflapon SCHEMBL1004174 | 0.99 | ALOX5 (1.00) | ALOX5HDAC6 | |
| Veliflapon SCHEMBL8798993 | 0.99 | ALOX5 (1.00) | ALOX5HDAC6 | |
| Veliflapon SCHEMBL502932 | 0.99 | ALOX5 (1.00) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716082-B1 | Oxy-phenyl-(phenyl)glycinolamides substituted with a bi-cycle having antiatherosclerotic activity | BAYER AG (DE) | 2001-03-07 | — | — | EP | disclosed |
| US-5691337-A | TREATING ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-25 | — | — | US | disclosed |
| US-5646162-A | ATHEROSCLEROSIS TREATMENT | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-08 | — | — | US | disclosed |
| EP-0716082-A1 | Oxy-phenyl-(phenyl)glycinolamides substituted with a heterocycle having antiatherosclerotic activity | BAYER AG (DE) | 1996-06-12 | — | — | EP | disclosed |