SCHEMBL72377

SCHEMBL72377

O=C(O)c1ccnc(C(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5C P41229 6/20 1.00
KDM4E B2RXH2 5/20 1.00
KDM4A O75164 5/20 1.00
KDM6B O15054 4/20 1.00
KDM2A Q9Y2K7 4/20 1.00
KDM3A Q9Y4C1 4/20 1.00
FTO Q9C0B1 4/20 1.00
KDM5B Q9UGL1 4/20 1.00
ALDH1A1 P00352 3/20 1.00
ALKBH5 Q6P6C2 3/20 1.00
KDM4C Q9H3R0 3/20 1.00
TET3 O43151 1/20 1.00
BBOX1 O75936 1/20 1.00
MAPT P10636 1/20 1.00
KDM5A P29375 1/20 1.00
ASPH Q12797 1/20 1.00
KDM4D Q6B0I6 1/20 1.00
TET2 Q6N021 1/20 1.00
KDM7A Q6ZMT4 1/20 1.00
KDM8 Q8N371 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382783 1.00 KDM5C (1.00) KDM5CKDM4EKDM4AKDM6BKDM2A
SCHEMBL28454743 0.98 KDM5C (0.96) KDM5CKDM4EKDM4AKDM6BKDM2A
SCHEMBL2276257 0.98 KDM5C (0.96) KDM5CKDM4EKDM4AKDM6BKDM2A
SCHEMBL27779659 0.98 KDM5C (0.96) KDM5CKDM4EKDM4AKDM6BKDM2A
Hydrochloric Acid SCHEMBL10778857 0.98 KDM5C (0.96) KDM5CKDM4EKDM4AKDM6BKDM2A
SCHEMBL9585966 0.98 KDM5C (0.96) KDM5CKDM4EKDM4AKDM6BKDM2A
SCHEMBL9585979 0.98 FTO (0.96) KDM5CKDM4EKDM4AKDM6BKDM2A
Water SCHEMBL2650345 0.98 KDM5C (0.96) KDM5CKDM4EKDM4AKDM6BKDM2A
Hydrochloric Acid SCHEMBL9361001 0.98 KDM5C (0.96) KDM5CKDM4EKDM4AKDM6BKDM2A
SCHEMBL29068424 0.89 KDM5C (0.79) KDM5CKDM4EKDM4AKDM6BKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2930 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739113-A1 COMPOSITION FOR USE IN AGRICULTURE Bayer Aktiengesellschaft (DE) 2026-05-13 EP claimed
EP-4547732-B1 POLYESTER POLYMER FOR USE IN HAIR CARE SYENSQO SA (BE) 2026-05-06 EP claimed
US-20260085336-A1 NEW POLYMERS AND METHODS BIOME BIOPLASTICS LTD (GB) 2026-03-26 US claimed
US-20260035512-A1 POLYAMIDES AND CORRESPONDING POLYMER COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING SYENSQO SPECIALTY POLYMERS USA, LLC (US) 2026-02-05 US claimed
US-12496357-B2 Compositions and methods for treating sickle cell disease YALE UNIVERSITY (US) 2025-12-16 US claimed
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US claimed
US-12473402-B2 Polyamides and corresponding polymer compositions, articles and methods for making and using SYENSQO SPECIALTY POLYMERS USA, LLC (US) 2025-11-18 US claimed
EP-4276136-B1 POLYAMIDES AND CORRESPONDING POLYMER COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING SYENSQO SPECIALTY POLYMERS USA LLC (US) 2025-11-12 EP claimed
US-12454710-B2 Process for the preparation of 2,4- or 2,5-pyridinedicarboxylic acid and copolymers derived therefrom BIOME BIOPLASTICS LIMITED (GB) 2025-10-28 US claimed
EP-4633909-A1 OVERMOLDED PLASTIC ARTICLES, USES THEREOF, METHOD OF MAKING Syensqo Specialty Polymers USA, LLC (US) 2025-10-22 EP claimed
EP-0161221-B1 PROCESS FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES AND OF 1-AMINO-1,4-DIHYDROPYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES CIBA-GEIGY AG (CH) 1991-07-10 EP claimed
US-5004748-A Substituted pyridine-2,4-dicarboxylic acid derivatives and medicaments based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1991-04-02 US claimed
EP-0409119-A1 N,N'-Bis(alkoxy-alkyl)-pyridine-2,4-dicarboxylic acid amides, process for their preparation as well as their use HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-23 EP claimed
EP-0353668-A2 Process for the preparation of N,N-bis(alkoxyalkyl) diamides of pyridine-2,4-dicarboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-07 EP claimed
EP-0300461-A2 Aromatic heterocyclic peroxyacids AUSIMONT S.p.A. (IT) 1989-01-25 EP claimed
EP-0145506-B1 ELIMINATION OF DEFECTS IN CYSTEINE-SENSITIZED EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-03-02 EP claimed
EP-0097551-B1 USE OF VANADIUM, NIOBIUM AND TANTALUM PEROXIDIC COMPLEXES AS REAGENTS AND CATALYSTS IN THE HYDROXYLATION OF AROMATIC HYDROCARBONS Institut Français du Pétrole (FR) 1986-10-15 EP claimed
US-4559291-A DIFFUSION TRANSFER ASSEMBLAGES USING REDOX DYE-RELEASERS, LIGUAND COMPETES FOR METAL TO METAL HYDROXIDE FORMATION EASTMAN KODAK COMPANY (US) 1985-12-17 US claimed
US-4529824-A Vanadium, niobium or tanatlum peroxidic complex INSTITUT FRANCAIS DU PETROLE (FR) 1985-07-16 US claimed
US-4130586-A Process for producing imine compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1978-12-19 US claimed