SCHEMBL9585966

SCHEMBL9585966

O=C(O)c1ccnc(C(=O)O)c1.[NaH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5C P41229 6/20 0.96
KDM4E B2RXH2 5/20 0.96
KDM4A O75164 5/20 0.96
FTO Q9C0B1 4/20 0.96
KDM6B O15054 4/20 0.96
KDM2A Q9Y2K7 4/20 0.96
KDM3A Q9Y4C1 4/20 0.96
KDM5B Q9UGL1 4/20 0.96
ALDH1A1 P00352 3/20 0.96
ALKBH5 Q6P6C2 3/20 0.96
KDM4C Q9H3R0 3/20 0.96
TET3 O43151 1/20 0.96
BBOX1 O75936 1/20 0.96
MAPT P10636 1/20 0.96
KDM5A P29375 1/20 0.96
ASPH Q12797 1/20 0.96
KDM4D Q6B0I6 1/20 0.96
TET2 Q6N021 1/20 0.96
KDM7A Q6ZMT4 1/20 0.96
KDM8 Q8N371 1/20 0.96

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382783 0.98 KDM5C (1.00) KDM5CKDM4EKDM4AFTOKDM6B
SCHEMBL72377 0.98 KDM5C (1.00) KDM5CKDM4EKDM4AFTOKDM6B
SCHEMBL9585979 0.96 FTO (0.96) KDM5CKDM4EKDM4AFTOKDM6B
SCHEMBL2276257 0.96 KDM5C (0.96) KDM5CKDM4EKDM4AFTOKDM6B
SCHEMBL27779659 0.96 KDM5C (0.96) KDM5CKDM4EKDM4AFTOKDM6B
SCHEMBL28454743 0.96 KDM5C (0.96) KDM5CKDM4EKDM4AFTOKDM6B
Water SCHEMBL2650345 0.96 KDM5C (0.96) KDM5CKDM4EKDM4AFTOKDM6B
Hydrochloric Acid SCHEMBL10778857 0.96 KDM5C (0.96) KDM5CKDM4EKDM4AFTOKDM6B
Hydrochloric Acid SCHEMBL9361001 0.96 KDM5C (0.96) KDM5CKDM4EKDM4AFTOKDM6B
SCHEMBL28460401 0.87 KDM5C (0.79) KDM5CKDM4EKDM4AFTOKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5238948-A Influence metabolism of collagen or biosynthesis of C1q HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-24 US disclosed