Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.44 |
| ▸ | CA2 | P00918 | 10/20 | 0.44 |
| ▸ | CA4 | P22748 | 8/20 | 0.44 |
| ▸ | CA9 | Q16790 | 8/20 | 0.44 |
| ▸ | CA12 | O43570 | 7/20 | 0.44 |
| ▸ | CA6 | P23280 | 7/20 | 0.44 |
| ▸ | CA5A | P35218 | 6/20 | 0.44 |
| ▸ | CA7 | P43166 | 6/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28021973 | 0.82 | AURKA (0.37) | CA1CA2CA4CA9CA12 | |
| SCHEMBL29384070 | 0.82 | AURKA (0.46) | CYP2C9APEX1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL29863001 | 0.82 | CA1 (0.34) | CA1CA2CA4CA9CA12 | |
| SCHEMBL338441 | 0.82 | AURKA (0.46) | CYP2C9APEX1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL579933 | 0.82 | CA1 (0.34) | CA1CA2CA4CA9CA12 | |
| SCHEMBL31229289 | 0.82 | AURKA (0.46) | CYP2C9APEX1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL29423956 | 0.80 | HSPD1 (0.43) | CYP2C9APEX1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL592094 | 0.80 | AURKA (0.45) | CYP2C9APEX1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL26638157 | 0.80 | AURKA (0.45) | CYP2C9APEX1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL592095 | 0.80 | HSPD1 (0.43) | CYP2C9APEX1CYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609426-B1 | FLUORESCENCE LABELING REAGENTS AND USES THEREOF | TEXAS A & M UNIV SYS (US) | 2018-12-19 | — | — | EP | disclosed |
| US-9896522-B2 | Solid phase fluorescence labeling reagents and uses thereof | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-02-20 | — | — | US | disclosed |
| US-20130224870-A1 | FLUORESCENCE LABELING REAGENTS AND USES THEREOF | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2013-08-29 | — | — | US | disclosed |
| EP-2609426-A2 | FLOURESCENCE LABELING REAGENTS AND USES THEREOF | The Texas A&M University System (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012027717-A2 | FLOURESCENCE LABELING REAGENTS AND USES THEREOF | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-03-01 | — | — | WO | disclosed |