Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | PLAT | P00750 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238146 | 1.00 | MTNR1A (0.51) | MTNR1AMTNR1BPLAUPLATPLG | |
| SCHEMBL7011450 | 0.80 | KDM1A (0.53) | MTNR1AMTNR1BPLAUPLATPLG | |
| SCHEMBL7231957 | 0.80 | KDM1A (0.53) | MTNR1AMTNR1BPLAUPLATPLG | |
| SCHEMBL7231439 | 0.80 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL7011682 | 0.80 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| Ammonia Solution, Strong SCHEMBL27532373 | 0.76 | PLAU (0.45) | MTNR1AMTNR1BPLAUPLATPLG | |
| SCHEMBL7235613 | 0.73 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL7007743 | 0.73 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL6246366 | 0.70 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL6245835 | 0.70 | MTNR1A (0.62) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |