Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050330 | 0.88 | LMNA (0.36) | KMT2AGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8530713 | 0.76 | KMT2A (0.39) | KMT2AGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8530445 | 0.74 | KMT2A (0.39) | KMT2AGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7052664 | 0.72 | KMT2A (0.37) | KMT2AGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29564074 | 0.71 | KMT2A (0.42) | KMT2AGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20457292 | 0.70 | PSMD10 (0.39) | KMT2AGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20107188 | 0.69 | KMT2A (0.38) | KMT2AGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3165478 | 0.67 | STAT3 (0.44) | KMT2AGAAALDH1A1MEN1STAT3 | |
| SCHEMBL10784623 | 0.67 | CA12 (0.41) | KMT2AGAALMNAALDH1A1KDM4E | |
| SCHEMBL2081536 | 0.66 | KMT2A (0.47) | KMT2AGAALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579890-B1 | Matrix metalloprotease inhibitors | SYNTEX (U.S.A.) INC. | 2003-06-17 | — | — | US | disclosed |
| EP-0793643-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016027-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-05-30 | — | — | WO | disclosed |