Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 3/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MTTP | P55157 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243455 | 0.95 | HTR7 (0.45) | HTR7HTR1ACCR1CCR3HTR4 | |
| SCHEMBL7238553 | 0.94 | HTR7 (0.43) | HTR7HTR1ASLC6A12CCR1CCR3 | |
| SCHEMBL7235483 | 0.94 | HTR7 (0.43) | HTR7HTR1ASLC6A12CCR1CCR3 | |
| SCHEMBL7237774 | 0.92 | KCNA3 (0.42) | HTR7HTR1ASLC6A12CCR1CCR3 | |
| SCHEMBL7242396 | 0.91 | HTR7 (0.41) | HTR7HTR1ASLC6A12CCR1CCR3 | |
| SCHEMBL7238486 | 0.90 | HTR7 (0.43) | HTR7HTR1ASLC6A12CCR1CCR3 | |
| SCHEMBL7241813 | 0.90 | HTR7 (0.46) | HTR7HTR1ASLC6A12CCR3HTR4 | |
| SCHEMBL7232202 | 0.89 | HTR7 (0.49) | HTR7CCR3CHRM2ADRA2AADORA3 | |
| SCHEMBL7570480 | 0.89 | SLC6A12 (0.48) | HTR7HTR1ASLC6A12CCR3UBE2M | |
| SCHEMBL7242757 | 0.89 | MTTP (0.42) | HTR7HTR1ACCR1CCR3HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617325-B1 | Inhibitors of the microsomal triglyceride-transfer protein | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-09-09 | — | — | US | disclosed |