Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7231358 | 0.98 | PREP (0.32) | PREPFAP | |
| SCHEMBL10413581 | 0.83 | ALDH1A1 (0.37) | — | |
| SCHEMBL30801954 | 0.80 | EPHX1 (0.38) | — | |
| SCHEMBL12496309 | 0.80 | EPHX1 (0.38) | — | |
| SCHEMBL23113551 | 0.79 | SLC6A1 (0.33) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL18150403 | 0.79 | SLC6A1 (0.33) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL15725266 | 0.78 | EPHX1 (0.37) | — | |
| SCHEMBL15741857 | 0.77 | CYP2D6 (0.33) | ALOX15SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL25590871 | 0.76 | PREP (0.38) | PREPFAPALOX15SLC6A1GABRA5 | |
| SCHEMBL10223278 | 0.76 | SLC6A1 (0.47) | PREPFAPALOX15SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531476-B1 | Block multiplication of virus within body and restore immune functions by virtue of inhibitory activity toward platelet activating factor | UNIVERSITE PARIS 7 - DENIS DIDEROT (FR) | 2003-03-11 | — | — | US | disclosed |