Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | BACE1 | P56817 | 3/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CCR5 | P51681 | 2/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029197 | 1.00 | BCHE (0.52) | BCHEACHEBACE1SLC18A3SIGMAR1 | |
| SCHEMBL7240145 | 1.00 | BCHE (0.52) | BCHEACHEBACE1SLC18A3SIGMAR1 | |
| SCHEMBL4029196 | 1.00 | BCHE (0.52) | BCHEACHEBACE1SLC18A3SIGMAR1 | |
| SCHEMBL4030955 | 1.00 | BCHE (0.52) | BCHEACHEBACE1SLC18A3SIGMAR1 | |
| SCHEMBL6576777 | 1.00 | BCHE (0.52) | BCHEACHEBACE1SLC18A3SIGMAR1 | |
| SCHEMBL7468131 | 0.91 | CCR5 (0.58) | BCHEACHEBACE1SIGMAR1CCR5 | |
| SCHEMBL7468128 | 0.91 | CCR5 (0.58) | BCHEACHEBACE1SIGMAR1CCR5 | |
| SCHEMBL7468123 | 0.91 | CCR5 (0.58) | BCHEACHEBACE1SIGMAR1CCR5 | |
| SCHEMBL7248619 | 0.88 | ACHE (0.53) | BCHEACHEBACE1SLC18A3SIGMAR1 | |
| SCHEMBL7248624 | 0.88 | ACHE (0.53) | BCHEACHEBACE1SLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6657062-B1 | Chemical intermediates for paroxetine derivatives; formylation, resolution, reduction, salt formation, catalysis | RICHTER GEDEON VEGYESSETI GYAR RT. (HU) | 2003-12-02 | — | — | US | disclosed |
| EP-0923554-B1 | N-BENZYLPIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | RICHTER GEDEON VEGYESZET (HU) | 2002-01-09 | — | — | EP | disclosed |
| EP-0923554-A1 | N-BENZYLPIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998001424-A1 | N-BENZYLPIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1998-01-15 | — | — | WO | disclosed |