Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723975 | 1.00 | KMT2A (0.43) | KMT2AALDH1A1CYP2C19HDAC3TNKS | |
| SCHEMBL15031819 | 0.86 | HDAC3 (0.37) | KMT2AALDH1A1CYP2C19HDAC3TNKS | |
| SCHEMBL725187 | 0.84 | CYP2C19 (0.48) | KMT2AALDH1A1CYP2C19HDAC3TNKS | |
| SCHEMBL725186 | 0.84 | CYP2C19 (0.48) | KMT2AALDH1A1CYP2C19HDAC3TNKS | |
| SCHEMBL28731805 | 0.79 | KMT2A (0.51) | KMT2AALDH1A1CYP2C19HDAC3TNKS | |
| SCHEMBL2518038 | 0.78 | TRPM8 (0.51) | KMT2AALDH1A1CYP2C19HDAC3TNKS | |
| SCHEMBL3255142 | 0.78 | TRPM8 (0.51) | KMT2AALDH1A1CYP2C19HDAC3TNKS | |
| SCHEMBL15006829 | 0.76 | CYP2C19 (0.49) | KMT2AALDH1A1CYP2C19HDAC3TNKS | |
| SCHEMBL15006830 | 0.76 | CYP2C19 (0.49) | KMT2AALDH1A1CYP2C19HDAC3TNKS | |
| SCHEMBL15418654 | 0.76 | CYP2C19 (0.49) | KMT2AALDH1A1CYP2C19HDAC3TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163114-B2 | Biodegradable shape memory polymer | UNIVERSITY OF MASSACHUSETTS (US) | 2015-10-20 | — | — | US | disclosed |
| US-9163114-B2 | Biodegradable shape memory polymer | UNIVERSITY OF MASSACHUSETTS (US) | 2015-10-20 | — | — | US | disclosed |
| US-20130150533-A1 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS | 2013-06-13 | — | — | US | disclosed |
| US-20130150533-A1 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS | 2013-06-13 | — | — | US | disclosed |
| WO-2012027573-A2 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012027573-A2 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150533-A1 | BIODEGRADABLE SHAPE MEMORY POLYMER | TLR1, SMC1A, PUF60 | KMT2A 2713/4885ALDH1A1 2762/4885CYP2C19 3125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.