SCHEMBL7239958

SCHEMBL7239958

COc1ccc(S(=O)(=O)N(CCC(=O)NO)CCc2ccc(OC)c(OC)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7008058 0.90 BMP1 (1.00) BMP1
SCHEMBL7000638 0.86 BMP1 (1.00) BMP1
SCHEMBL7003452 0.85 BMP1 (0.89) BMP1
SCHEMBL7004497 0.85 BMP1 (0.89) BMP1
SCHEMBL7111482 0.82 BMP1 (1.00) BMP1
SCHEMBL7004835 0.82 BMP1 (1.00) BMP1
SCHEMBL7001896 0.81 BMP1 (1.00) BMP1
SCHEMBL7008077 0.80 BMP1 (0.77) BMP1
SCHEMBL27558816 0.80 BMP1 (0.79) BMP1
SCHEMBL7109267 0.80 BMP1 (1.00) BMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6506936-B1 Treating fibrotic disorder selected from hepatic cirrhosis and arthritis; inhibiting matrix metalloproteases FIBROGEN, INC. 2003-01-14 US claimed