SCHEMBL7111482

SCHEMBL7111482

COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(/C(N)=N/O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7004835 1.00 BMP1 (1.00) BMP1
SCHEMBL7004238 0.89 BMP1 (1.00) BMP1
SCHEMBL7110675 0.89 BMP1 (1.00) BMP1
SCHEMBL7008058 0.89 BMP1 (1.00) BMP1
SCHEMBL7000638 0.85 BMP1 (1.00) BMP1
SCHEMBL7231482 0.84 BMP1 (0.72) BMP1
SCHEMBL7231486 0.84 BMP1 (0.72) BMP1
SCHEMBL7003452 0.84 BMP1 (0.89) BMP1
SCHEMBL7004497 0.84 BMP1 (0.89) BMP1
SCHEMBL7233209 0.83 BMP1 (1.00) BMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6506936-B1 Treating fibrotic disorder selected from hepatic cirrhosis and arthritis; inhibiting matrix metalloproteases FIBROGEN, INC. 2003-01-14 US claimed
US-20030191309-A1 N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of C-proteinase and for treating or preventing disorders related to unregulated collagen production HO WEN-BIN (US) 2003-10-09 US disclosed
US-6506936-B1 Treating fibrotic disorder selected from hepatic cirrhosis and arthritis; inhibiting matrix metalloproteases FIBROGEN, INC. 2003-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191309-A1 N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of C-proteinase and for treating or preventing disorders related to unregulated collagen production MMP1, MMP13, COL14A1 BMP1 730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.