SCHEMBL724134

SCHEMBL724134

Cc1ccc2c(C)cc(=O)oc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.68
KDM4E B2RXH2 9/20 0.68
HPGD P15428 6/20 0.68
HSD17B10 Q99714 6/20 0.68
CA9 Q16790 6/20 0.68
GLA P06280 5/20 0.68
GAA P10253 5/20 0.68
CA12 O43570 5/20 0.68
CA1 P00915 4/20 0.68
CASP1 P29466 3/20 0.68
CASP7 P55210 3/20 0.68
LMNA P02545 2/20 0.68
AKR1B1 P15121 2/20 0.68
MCL1 Q07820 2/20 0.68
MAOB P27338 2/20 0.68
CYP1A2 P05177 1/20 0.68
CYP2C9 P11712 1/20 0.68
UGT1A1 P22309 1/20 0.68
KDR P35968 1/20 0.68
HSD17B3 P37058 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30117164 0.98 ALDH1A1 (0.66) ALDH1A1KDM4EHPGDHSD17B10CA9
SCHEMBL19427475 0.85 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDHSD17B10CA9
SCHEMBL14424517 0.84 CA12 (0.61) ALDH1A1KDM4EHPGDHSD17B10CA9
SCHEMBL30636721 0.84 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10CA9
SCHEMBL8750160 0.84 ALDH1A1 (0.58) ALDH1A1KDM4EHPGDHSD17B10CA9
SCHEMBL67818 0.84 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10CA9
SCHEMBL30424058 0.82 ALDH1A1 (0.66) ALDH1A1KDM4EHPGDHSD17B10CA9
SCHEMBL6385935 0.82 ALDH1A1 (0.66) ALDH1A1KDM4EHPGDHSD17B10CA9
SCHEMBL2053821 0.82 NQO1 (0.58) ALDH1A1KDM4EHPGDHSD17B10CA9
SCHEMBL31463116 0.82 NPC1 (0.49) ALDH1A1KDM4EHPGDHSD17B10CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954761-A Method for synthesizing 4-aldehyde-7-methylcoumarin by microwave-assisted method 齐齐哈尔大学 2025-05-09 CN claimed
CN-108911951-B Thymol and preparation method and pharmaceutical composition thereof 漳州水仙药业股份有限公司 2021-05-14 CN claimed
US-9127092-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2015-09-08 US claimed
US-20140187725-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2014-07-03 US claimed
US-20130225870-A1 METHOD OF SYNTHESIZING SUBSTITUTED 2-ALKYL PHENOLS SYNTA PHARMACEUTICALS CORP. (US) 2013-08-29 US claimed
WO-2012026931-A1 METHOD OF SYNTHESIZING SUBSTITUTED 2-ALKYL PHENOLS SYNTA PHARMACEUTICALS CORP. (US) 2012-03-01 WO claimed
CN-119954761-A Method for synthesizing 4-aldehyde-7-methylcoumarin by microwave-assisted method 齐齐哈尔大学 2025-05-09 CN disclosed
CN-119954761-A Method for synthesizing 4-aldehyde-7-methylcoumarin by microwave-assisted method 齐齐哈尔大学 2025-05-09 CN disclosed
EP-3597673-B1 PHOTOCROSSLINKABLE POLYMER, INSULATING FILM, PLANARIZATION FILM, LYOPHILIC/LIQUID REPELLENT PATTERNED FILM, AND ORGANIC FIELD EFFECT TRANSISTOR DEVICE COMPRISING SAME TOSOH CORP (JP) 2023-06-07 EP disclosed
CN-111499497-B Preparation method of thymol 漳州水仙药业股份有限公司 2022-11-01 CN disclosed
US-20220323528-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS CARGILL, INCORPORATED (US) 2022-10-13 US disclosed
US-20220145339-A1 METHOD FOR PREPARATION OF PRIMARY AMINE COMPOUNDS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2022-05-12 US disclosed
US-20220017940-A1 FLUORESCENT PROBE FOR DETECTING CARBOXYPEPTIDASE ACTIVITY THE UNIVERSITY OF TOKYO (JP) 2022-01-20 US disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed
EP-1757607-A1 N5-substituted benzo¬2,3|azepino¬4,5-b|indol-6-ones for treating tropical diseases Molisa GmbH (DE) 2007-02-28 EP disclosed
CN-1896244-A Guinea pig chymase HOFFMANN LA ROCHE (CH) 2007-01-17 CN disclosed
WO-2005023818-A2 HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS GPC BIOTECH AG (DE) 2005-03-17 WO disclosed
CN-1147589-C Method for detecting flu A-type and B-type in clinic sample �����������ҽѧ�о������ 2004-04-28 CN disclosed
CN-1324954-A Method for detecting flu A-type and B-type in clinic sample OKLAHOMA STATE MEDICAL RES FOU (US) 2001-12-05 CN disclosed
CN-1205011-A 4, 7-dialkoxy N-acetylneuraminic acid derivatives and methods for their use in clinical samples for the detection of influenza type A and B viruses OKLAHOMA MED RES FOUND (US) 1999-01-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220323528-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS SI, TAS2R7, TAS2R31 ALDH1A1 2625/4885KDM4E 3664/4885HPGD 524/4885
US-20130225870-A1 METHOD OF SYNTHESIZING SUBSTITUTED 2-ALKYL PHENOLS CYP4B1, CYP4A11, CYP4X1 ALDH1A1 417/4885KDM4E 640/4885HPGD 973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.