SCHEMBL724240

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL723230	0.91	JAK1 (0.54)	PIK3CDERN1POLBALDH1A1JAK2
	SCHEMBL30765331	0.91	JAK1 (0.54)	PIK3CDERN1POLBALDH1A1JAK2
	SCHEMBL723296	0.90	JAK2 (0.50)	PIK3CDPIK3CAPIK3CBPIK3CGKCNH2
	SCHEMBL725175	0.86	ACVR1 (0.42)	ALDH1A1JAK2JAK1TYK2JAK3
	SCHEMBL722851	0.84	PDE4C (0.46)	ERN1JAK2JAK1TYK2JAK3
	SCHEMBL724085	0.84	PDE4C (0.45)	ERN1JAK2JAK1TYK2JAK3
	SCHEMBL27920235	0.83	JAK1 (0.40)	PIK3CDPIK3CAALDH1A1JAK2JAK1
	SCHEMBL722515	0.83	ACVR1 (0.47)	ALDH1A1CYP1A2KDM4EFYN
	SCHEMBL724106	0.82	PDE4C (0.44)	JAK2JAK1TYK2JAK3L3MBTL1
	SCHEMBL27261394	0.82	L3MBTL1 (0.43)	PIK3CDPIK3CAPIK3CBPIK3CGKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.