Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GPR183 | P32249 | 8/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724264 | 1.00 | MEN1 (0.54) | MEN1KMT2AGPR183FAAHACHE | |
| SCHEMBL1486971 | 0.84 | GPR183 (0.52) | MEN1KMT2AGPR183FAAHACHE | |
| SCHEMBL1486969 | 0.84 | GPR183 (0.52) | MEN1KMT2AGPR183FAAHACHE | |
| SCHEMBL723187 | 0.84 | CA12 (0.51) | MEN1KMT2AGPR183HDAC3HDAC4 | |
| SCHEMBL723186 | 0.84 | CA12 (0.51) | MEN1KMT2AGPR183HDAC3HDAC4 | |
| SCHEMBL724438 | 0.84 | HDAC1 (0.65) | MEN1KMT2AGPR183FAAHHDAC3 | |
| SCHEMBL18841330 | 0.83 | CA12 (0.50) | MEN1KMT2AGPR183ACHEHDAC3 | |
| SCHEMBL2232758 | 0.82 | FAAH (0.50) | MEN1KMT2AGPR183FAAHACHE | |
| SCHEMBL2232762 | 0.82 | FAAH (0.50) | MEN1KMT2AGPR183FAAHACHE | |
| SCHEMBL18841352 | 0.81 | BCHE (0.49) | ACHEHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025155-A1 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES | NOVARTIS AG (CH) | 2012-03-01 | — | — | WO | disclosed |