Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | STAT3 | P40763 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | HTR1E | P28566 | 1/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244907 | 0.88 | SMN1; SMN2 (0.66) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL7242115 | 0.85 | NLRP3 (0.69) | LMNASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL7238120 | 0.84 | USP2 (0.67) | SMN1; SMN2KMT2AALDH1A1MEN1TP53 | |
| SCHEMBL7239156 | 0.83 | USP2 (0.57) | SMN1; SMN2KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL3653095 | 0.82 | EPHX2 (0.77) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL7239646 | 0.81 | NLRP3 (0.67) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7236516 | 0.81 | NLRP3 (0.59) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7246958 | 0.81 | KMT2A (0.72) | LMNASMN1; SMN2KMT2AKDM4EEPHX2 | |
| SCHEMBL7168527 | 0.81 | L3MBTL1 (0.69) | LMNASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL7238522 | 0.80 | NLRP3 (0.65) | LMNASMN1; SMN2HTTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083523-A1 | Amide derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-05-01 | — | — | US | disclosed |
| US-6444849-B1 | BACTERICIDES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-09-03 | — | — | US | disclosed |
| EP-0887341-A1 | Amide derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083523-A1 | Amide derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, CBR1 | LMNA 1674/4885SMN1; SMN2 4084/4885HTT 3248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.