Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GALR3 | O60755 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7237041 | 0.88 | MAPT (0.78) | MAPTKCNH2LMNAALDH1A1KMT2A | |
| SCHEMBL2958454 | 0.86 | HIF1A (0.71) | MAPTLMNAGALR3STAT3ALDH1A1 | |
| SCHEMBL7243115 | 0.83 | KCNH2 (0.68) | MAPTKCNH2LMNAALDH1A1KMT2A | |
| SCHEMBL7239320 | 0.82 | DAPK1 (0.77) | MAPTKCNH2LMNAALDH1A1SIRT5 | |
| SCHEMBL4738194 | 0.82 | GALR3 (0.79) | MAPTLMNAGALR3STAT3ALDH1A1 | |
| SCHEMBL7168527 | 0.81 | L3MBTL1 (0.69) | MAPTLMNAALDH1A1SIRT5KMT2A | |
| SCHEMBL7238805 | 0.80 | RAB9A (0.78) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7244929 | 0.80 | SMN1; SMN2 (0.64) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL25463130 | 0.79 | RAB9A (0.72) | LMNAGALR3STAT3ALDH1A1KMT2A | |
| SCHEMBL2332894 | 0.79 | GALR3 (0.66) | LMNAGALR3STAT3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083523-A1 | Amide derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-05-01 | — | — | US | claimed |
| EP-0887341-A1 | Amide derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-12-30 | — | — | EP | claimed |
| US-20030083523-A1 | Amide derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-05-01 | — | — | US | disclosed |
| US-6444849-B1 | BACTERICIDES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-09-03 | — | — | US | disclosed |
| EP-0887341-A1 | Amide derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083523-A1 | Amide derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, CBR1 | MAPT 3965/4885KCNH2 228/4885LMNA 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.