Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244964 | 0.76 | ADORA2A (0.33) | ALDH1A1PKMKDM4EMAPTHPGD | |
| SCHEMBL7248984 | 0.74 | NPSR1 (0.44) | ALDH1A1KDM4EMAPTNPSR1HSD17B10 | |
| SCHEMBL7241569 | 0.71 | MEN1 (0.39) | ALDH1A1PKMKDM4EMAPTLMNA | |
| SCHEMBL7244214 | 0.69 | MEN1 (0.38) | ALDH1A1PKMKDM4EMAPTLMNA | |
| SCHEMBL7246718 | 0.68 | MEN1 (0.46) | ALDH1A1PKMKDM4EMAPTLMNA | |
| SCHEMBL6998612 | 0.68 | KDM4E (0.50) | ALDH1A1KDM4ELMNANPSR1MEN1 | |
| SCHEMBL7036441 | 0.66 | MEN1 (0.64) | ALDH1A1PKMKDM4EMAPTLMNA | |
| SCHEMBL7036685 | 0.66 | ADORA2A (0.46) | ALDH1A1PKMKDM4EMAPTLMNA | |
| SCHEMBL7041221 | 0.66 | ADORA2A (0.42) | ALDH1A1KDM4EMAPTLMNANPSR1 | |
| SCHEMBL15104852 | 0.64 | CCNC (0.47) | ALDH1A1PKMKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TST, STS, AHR | ALDH1A1 327/4885PKM 2964/4885KDM4E 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.