Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CASP6 | P55212 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL8967197 | 0.97 | MEN1 (0.59) | MEN1KMT2ATSHRTDP1CASP6 | |
| SCHEMBL8960516 | 0.83 | CASP6 (0.64) | MEN1KMT2ATSHRCASP6HCAR3 | |
| SCHEMBL30714879 | 0.83 | CASP6 (0.64) | MEN1KMT2ATSHRCASP6HCAR3 | |
| SCHEMBL11052022 | 0.82 | PTPN1 (0.58) | MEN1KMT2ATSHRTDP1CASP6 | |
| SCHEMBL10945219 | 0.80 | CASP6 (0.62) | MEN1KMT2ATSHRTDP1CASP6 | |
| SCHEMBL27787852 | 0.80 | CASP6 (0.50) | MEN1KMT2ATSHRCASP6ALDH1A1 | |
| SCHEMBL27787693 | 0.80 | CASP6 (0.50) | MEN1KMT2ATSHRCASP6ALDH1A1 | |
| SCHEMBL27787689 | 0.80 | CASP6 (0.50) | MEN1KMT2ATSHRTDP1CASP6 | |
| SCHEMBL10708315 | 0.77 | TDP1 (0.66) | MEN1KMT2ATSHRTDP1CASP6 | |
| SCHEMBL5148419 | 0.77 | KMT2A (1.00) | MEN1KMT2AALDH1A1HCAR3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497441-C | Polyimide containing isoscrbierite unit and its preparing method | UNIV TSINGHUA (CN) | 2009-06-10 | — | — | CN | claimed |
| CN-1289504-C | Diamine monomer containing di-dehydrated hexitol unit and its preparing method | UNIV TSINGHUA (CN) | 2006-12-13 | — | — | CN | claimed |
| CN-1616462-A | Diamine monomer containing di-dehydrated hexitol unit and its preparing method | UNIV TSINGHUA (CN) | 2005-05-18 | — | — | CN | claimed |
| CN-1616521-A | Polyimide containing isoscrbierite unit and its preparing method | UNIV TSINGHUA (CN) | 2005-05-18 | — | — | CN | claimed |
| CN-100497441-C | Polyimide containing isoscrbierite unit and its preparing method | UNIV TSINGHUA (CN) | 2009-06-10 | — | — | CN | disclosed |
| CN-1289504-C | Diamine monomer containing di-dehydrated hexitol unit and its preparing method | UNIV TSINGHUA (CN) | 2006-12-13 | — | — | CN | disclosed |
| CN-1616462-A | Diamine monomer containing di-dehydrated hexitol unit and its preparing method | UNIV TSINGHUA (CN) | 2005-05-18 | — | — | CN | disclosed |
| CN-1616521-A | Polyimide containing isoscrbierite unit and its preparing method | UNIV TSINGHUA (CN) | 2005-05-18 | — | — | CN | disclosed |
| US-6541491-B1 | Treating ras mediated diseases, especially cancer. | ZENECA LIMITED (GB) | 2003-04-01 | — | — | US | disclosed |
| US-6232338-B1 | 4-Mercaptopyrrolidine derivatives as farnesyl transferase inhibitors | ZENECA LIMITED (GB) | 2001-05-15 | — | — | US | disclosed |
| EP-0842151-A1 | 4-MERCAPTOPYRROLIDINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997006138-A1 | 4-MERCAPTOPYRROLIDINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1997-02-20 | — | — | WO | disclosed |