Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243262 | 0.97 | MEN1 (0.62) | MEN1KMT2ATSHRTDP1CASP6 | |
| SCHEMBL8960516 | 0.81 | CASP6 (0.64) | MEN1KMT2ATSHRCASP6HCAR3 | |
| SCHEMBL30714879 | 0.81 | CASP6 (0.64) | MEN1KMT2ATSHRCASP6HCAR3 | |
| SCHEMBL11052022 | 0.79 | PTPN1 (0.58) | MEN1KMT2ATSHRTDP1CASP6 | |
| SCHEMBL10945219 | 0.77 | CASP6 (0.62) | MEN1KMT2ATSHRTDP1CASP6 | |
| SCHEMBL27787852 | 0.77 | CASP6 (0.50) | MEN1KMT2ATSHRCASP6ALDH1A1 | |
| SCHEMBL27787693 | 0.77 | CASP6 (0.50) | MEN1KMT2ATSHRCASP6ALDH1A1 | |
| SCHEMBL27787689 | 0.77 | CASP6 (0.50) | MEN1KMT2ATSHRTDP1CASP6 | |
| SCHEMBL3388906 | 0.76 | PTGER4 (0.54) | MEN1KMT2ATSHRALDH1A1TPMT | |
| SCHEMBL6915188 | 0.75 | PTGER4 (0.52) | MEN1KMT2ATSHRALDH1A1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585116-B1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LTD (GB) | 1996-02-28 | — | — | EP | disclosed |
| US-5389684-A | Treats disorder of central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| EP-0585116-A1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |