Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153190 | 0.94 | SMN1; SMN2 (0.37) | POLBSMN1; SMN2ALDH1A1HRH3MEN1 | |
| SCHEMBL6153062 | 0.93 | HPGD (0.34) | ALDH1A1HRH3L3MBTL1KDM4EMEN1 | |
| SCHEMBL6152882 | 0.89 | POLB (0.39) | POLBSMN1; SMN2ALDH1A1HRH3L3MBTL1 | |
| SCHEMBL6152510 | 0.83 | POLB (0.33) | POLBSMN1; SMN2HRH3L3MBTL1KDM4E | |
| SCHEMBL6152414 | 0.82 | PTAFR (0.37) | HRH3L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL6152961 | 0.81 | HTR1A (0.30) | — | |
| SCHEMBL6153461 | 0.80 | CYP4F2 (0.34) | POLBSMN1; SMN2ALDH1A1KDM4ETP53 | |
| SCHEMBL6152973 | 0.80 | PTAFR (0.32) | POLBSMN1; SMN2HRH3MEN1KMT2A | |
| SCHEMBL6153189 | 0.79 | CYP2C9 (0.32) | POLBSMN1; SMN2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7245220 | 0.79 | TBXA2R (0.47) | SMN1; SMN2ALDH1A1KDM4ETP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653313-B2 | For treatment and prevention of inflammation, asthma, allergic rhinitis, pain and other disorders | WARNER-LAMBERT COMPANY LLC | 2003-11-25 | — | — | US | disclosed |