Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15227744 | 0.84 | TRPM8 (0.41) | TRPM8SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL21319123 | 0.75 | MCL1 (0.58) | TRPM8SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL30758143 | 0.75 | MCL1 (0.58) | TRPM8SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL22272362 | 0.74 | MAPT (0.53) | TRPM8SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL4787524 | 0.74 | MAPT (0.50) | SMN1; SMN2MAPTLMNAHTTRAB9A | |
| SCHEMBL8343910 | 0.73 | MAPT (0.34) | TRPM8SMN1; SMN2MAPTLMNAHTT | |
| Cinnamic Acid SCHEMBL3714627 | 0.72 | HCAR2 (0.61) | TRPM8SMN1; SMN2MAPTLMNANPC1 | |
| Cinnamic Acid SCHEMBL3714625 | 0.72 | HCAR2 (0.61) | TRPM8SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL14249431 | 0.71 | POLB (0.39) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL22272366 | 0.71 | MAPT (0.53) | TRPM8SMN1; SMN2MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163114-B2 | Biodegradable shape memory polymer | UNIVERSITY OF MASSACHUSETTS (US) | 2015-10-20 | — | — | US | disclosed |
| US-20130150533-A1 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS | 2013-06-13 | — | — | US | disclosed |
| WO-2012027573-A2 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150533-A1 | BIODEGRADABLE SHAPE MEMORY POLYMER | TLR1, SMC1A, PUF60 | TRPM8 4522/4885SMN1; SMN2 178/4885MAPT 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.