Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 13/20 | 0.90 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.64 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834991 | 0.94 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7246114 | 0.83 | FKBP1A (0.90) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL5834377 | 0.80 | FKBP1A (0.94) | FKBP1A | |
| SCHEMBL6100156 | 0.79 | FKBP1A (0.74) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL4679872 | 0.79 | FKBP1A (0.74) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7761780 | 0.78 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| Gpi-1046 SCHEMBL4766380 | 0.78 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| Gpi-1046 SCHEMBL7187 | 0.78 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL5833657 | 0.78 | FKBP1A (0.83) | FKBP1A | |
| SCHEMBL5965941 | 0.77 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6544976-B1 | Treating disorders characterized by neuronal damage caused by disease or trauma, such as Parkinson's disease, Alzheimer's disease, stroke, multiple sclerosis, amyotrophic lateral sclerosis, diabetic neuropathy and Bell's palsy. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-04-08 | — | — | US | disclosed |