SCHEMBL7246113

SCHEMBL7246113

CCC(Oc1ccccc1)C(=O)OP(CC)CC

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
TSHR P16473 2/20 0.47
NPSR1 Q6W5P4 1/20 0.44
PPARG P37231 2/20 0.43
PPARA Q07869 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HSD17B10 Q99714 2/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10552330 0.82 ALDH1A1 (0.52) ALDH1A1TSHRNPSR1PPARGPPARA
SCHEMBL767041 0.80 TDP1 (0.55) ALDH1A1TSHRNPSR1PPARGPPARA
SCHEMBL16672960 0.80 TSHR (0.55) ALDH1A1TSHRNPSR1PPARGPPARA
SCHEMBL10938219 0.80 TSHR (0.58) ALDH1A1TSHRNPSR1PPARGPPARA
SCHEMBL27635948 0.79 ALDH1A1 (0.50) ALDH1A1TSHRNPSR1PPARGPPARA
SCHEMBL295888 0.78 SMN1; SMN2 (0.64) ALDH1A1TSHRPPARGPPARASMN1; SMN2
SCHEMBL4651839 0.78 SMN1; SMN2 (0.64) ALDH1A1TSHRPPARGPPARASMN1; SMN2
SCHEMBL10361229 0.78 ALDH1A1 (0.59) ALDH1A1TSHRNPSR1PPARGPPARA
SCHEMBL16673220 0.78 LMNA (0.50) ALDH1A1TSHRNPSR1PPARGPPARA
SCHEMBL11131627 0.76 ALDH1A1 (0.54) ALDH1A1TSHRNPSR1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6608194-B1 Hypolipidemic, antihyperglycemic, antiobesity and hypocholes-terolemic agents DR. REDDY'S LABORATORIES LIMITED (IN) 2003-08-19 US disclosed
US-6548666-B1 Phenazine, phenoxazine, or phenothiazine derivatives; antilipemic, hypoglycemic, anticholesterol and antiobesity agents DR. REDDY'S RESEARCH FOUNDATION (IN) 2003-04-15 US disclosed
US-6440961-B1 Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them DR. REDDY'S RESEARCH FOUNDATION (IN) 2002-08-27 US disclosed
EP-1155006-A1 NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM Dr. Reddy's Research Foundation (IN) 2001-11-21 EP disclosed
WO-2000050414-A1 NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM DR.REDDY'S RESEARCH FOUNDATION (IN) 2000-08-31 WO disclosed