Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246980 | 0.89 | PRMT6 (0.43) | PRMT6P2RY12BMPR1BP2RY2P2RY1 | |
| SCHEMBL7246178 | 0.85 | P2RY12 (0.44) | PRMT6P2RY12BMPR1BP2RY2P2RY1 | |
| SCHEMBL30209516 | 0.77 | P2RY12 (0.51) | PRMT6P2RY12BMPR1BP2RY2P2RY1 | |
| SCHEMBL7067714 | 0.76 | P2RY12 (0.43) | PRMT6P2RY12BMPR1BP2RY2P2RY1 | |
| SCHEMBL31723494 | 0.73 | P2RY12 (0.50) | PRMT6P2RY12BMPR1BP2RY2P2RY1 | |
| SCHEMBL16940281 | 0.73 | PRMT6 (0.51) | PRMT6P2RY12BMPR1BP2RY2P2RY1 | |
| SCHEMBL38653713 | 0.73 | ADORA1 (0.56) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL19407591 | 0.73 | ADORA1 (0.56) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL19399423 | 0.73 | PRMT6 (0.51) | PRMT6P2RY12BMPR1BP2RY2P2RY1 | |
| SCHEMBL7064871 | 0.73 | ADORA1 (0.56) | ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6639062-B2 | Oligonucleotides which elicit ribonuclease for cleavage in complementary nucleic acid strand, having increased binding affinity/nuclease resistance; for medical diagnosis, gene therapy | ISIS PHARMACEUTICALS, INC. | 2003-10-28 | — | — | US | disclosed |
| US-6420549-B1 | NUCLEOTIDE SEQUENCES FOR USE AS TOOLS IN GENETIC ENGINEERING AND CONTROLLING TRANSLATION | ISIS PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |