Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3990847 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL6830322 | 0.78 | — | — | |
| SCHEMBL27967167 | 0.78 | — | — | |
| Tetrahydrofuran SCHEMBL29066948 | 0.74 | HTT (0.40) | HTTALDH1A1NPC1RAB9AMAPT | |
| Tetrahydrofuran SCHEMBL27927339 | 0.74 | HTT (0.40) | HTTALDH1A1NPC1RAB9AMAPT | |
| Tetrahydrofuran SCHEMBL27873625 | 0.74 | HTT (0.40) | HTTALDH1A1NPC1RAB9AMAPT | |
| Tetrahydrofuran SCHEMBL27873622 | 0.72 | HTT (0.42) | HTTALDH1A1MAPTHPGDKDM4E | |
| Tetrahydrofuran SCHEMBL28941093 | 0.72 | ALDH1A1 (0.42) | ALDH1A1 | |
| Tetrahydrofuran SCHEMBL27840656 | 0.67 | ALDH1A1 (0.42) | HTTALDH1A1NPC1RAB9AMAPT | |
| Benzene SCHEMBL1051803 | 0.63 | ALDH1A1 (0.73) | HTTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2947066-B1 | PHENOXYALKYLAMINE COMPOUND | UNIV OSAKA (JP) | 2018-09-19 | — | — | EP | disclosed |
| CN-105263899-B | Phenoxyalkylamine compound | 国立大学法人大阪大学 | 2017-11-14 | — | — | CN | disclosed |
| US-9771316-B2 | Phenoxyalkylamine compound | OSAKA UNIVERSITY (JP) | 2017-09-26 | — | — | US | disclosed |
| US-20150336876-A1 | PHENOXYALKYLAMINE COMPOUND | KNC LABORATORIES CO., LTD. (JP) | 2015-11-26 | — | — | US | disclosed |
| EP-2947066-A1 | PHENOXYALKYLAMINE COMPOUND | Osaka University (JP) | 2015-11-25 | — | — | EP | disclosed |
| US-20030220368-A1 | Novel piperidine compouds and drugs containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2003-11-27 | — | — | US | disclosed |
| CN-1395575-A | Novel piperidine compounds and drugs containing the same | EISAI CO LTD (JP) | 2003-02-05 | — | — | CN | disclosed |
| EP-1254904-A1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5100575-A | Thermally stable, reactive organometallic compositions containing copper | FMC CORPORATION (US) | 1992-03-31 | — | — | US | disclosed |
| WO-1991011494-A1 | THERMALLY STABLE, REACTIVE ORGANOMETALLIC COMPOSITIONS CONTAINING COPPER | FMC CORPORATION (US) | 1991-08-08 | — | — | WO | disclosed |
| WO-1990002781-A1 | THERMALLY STABLE, REACTIVE ORGANOMETALLIC COMPOSITIONS CONTAINING COPPER | LITHIUM CORPORATION OF AMERICA (US) | 1990-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336876-A1 | PHENOXYALKYLAMINE COMPOUND | LATS1, LATS2, SHC1 | HTT 2305/4885ALDH1A1 1157/4885NPC1 1713/4885 |
| US-20030220368-A1 | Novel piperidine compouds and drugs containing the same | TRPV1, CACNA1D, KCND2 | HTT 522/4885ALDH1A1 408/4885NPC1 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.