Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.84 |
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | HPGD | P15428 | 2/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.84 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.84 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.84 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosmet SCHEMBL3620 | 0.92 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL29350557 | 0.92 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL1663406 | 0.92 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL28101067 | 0.83 | ALDH1A1 (0.82) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| SCHEMBL13596981 | 0.82 | ALDH1A1 (0.81) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL15561615 | 0.81 | ALDH1A1 (0.78) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL28129898 | 0.79 | ALDH1A1 (0.74) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL27825696 | 0.79 | ALDH1A1 (0.74) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL428639 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| SCHEMBL11554380 | 0.77 | HPGD (0.73) | ALDH1A1MAPTHPGDALOX15PLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613769-B1 | Incubating samples with enzyme inhibitors, then determining complexes formed; medical diagnosis; therapy for allergies and inflammation | Max-Planck-Gesellschaft zur Föderung der Wissenschaften. e.V. (DE) | 2003-09-02 | — | — | US | disclosed |