Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.63 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.63 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.63 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosmet SCHEMBL1663406 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL29350557 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL3620 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Phosmet SCHEMBL7246728 | 0.78 | ALDH1A1 (0.84) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| SCHEMBL2130589 | 0.73 | GRIK1 (0.73) | GRIK1MAPK1TDP1LTA4HNOS1 | |
| SCHEMBL5082998 | 0.73 | GRIK1 (0.73) | GRIK1MAPK1TDP1LTA4HNOS1 | |
| SCHEMBL377574 | 0.73 | GRIK1 (0.73) | GRIK1MAPK1TDP1LTA4HNOS1 | |
| Phosmet SCHEMBL15561615 | 0.72 | ALDH1A1 (0.78) | ALDH1A1MAPTHPGDALOX15PLIN1 | |
| Hydrochloric Acid SCHEMBL7359673 | 0.71 | GRIK1 (0.71) | GRIK1MAPK1TDP1LTA4HNOS1 | |
| Hydrochloric Acid SCHEMBL27975738 | 0.71 | GRIK1 (0.71) | GRIK1MAPK1TDP1LTA4HNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883963-B2 | Peptidomimetics with glucagon antagonistic and GLP 1 agonistic activities | CADILA HEALTHCARE LIMITED (IN) | 2014-11-11 | — | — | US | disclosed |
| US-8383581-B2 | Short-chain peptides as parathyroid hormone (PTH) receptor agonist | CADILA HEALTHCARE LIMITED (IN) | 2013-02-26 | — | — | US | disclosed |
| US-20120264685-A1 | SHORT CHAIN PEPTIDOMIMETICS BASED ORALLY ACTIVE GLP 1 AGONIST AND GLUCAGON RECEPTOR ANTAGONIST | CADILA HEALTHCARE LIMITED (IN) | 2012-10-18 | — | — | US | disclosed |
| WO-2012120532-A2 | CYCLIC SHORT CHAIN PEPTIDES | CADILA HEALTHCARE LIMITED (IN) | 2012-09-13 | — | — | WO | disclosed |
| US-20120108496-A1 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
| EP-2231701-B1 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES | CADILA HEALTHCARE LTD (IN) | 2012-04-18 | — | — | EP | disclosed |
| EP-2421893-A2 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | Cadila Healthcare Limited (IN) | 2012-02-29 | — | — | EP | disclosed |
| US-20120021972-A1 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP 1 AGONISTIC ACTIVITIES | CADILA HEALTHCARE LIMITED (IN) | 2012-01-26 | — | — | US | disclosed |
| WO-2010128521-A2 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |
| EP-2231701-A2 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES | Cadila Healthcare Limited (IN) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009125424-A2 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES | CADILA HEALTHCARE LIMITED (IN) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108496-A1 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | PTH1R, GIPR, PTMS | ALDH1A1 3467/4885MAPT 4729/4885HPGD 668/4885 |
| US-20120264685-A1 | SHORT CHAIN PEPTIDOMIMETICS BASED ORALLY ACTIVE GLP 1 AGONIST AND GLUCAGON RECEPTOR ANTAGONIST | GIPR, GLP1R, DPP4 | ALDH1A1 2704/4885MAPT 4604/4885HPGD 1540/4885 |
| US-20120021972-A1 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP 1 AGONISTIC ACTIVITIES | GLP1R, GPR119, GIPR | ALDH1A1 3147/4885MAPT 4741/4885HPGD 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.