Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.53 |
| ▸ | TERT | O14746 | 4/20 | 0.42 |
| ▸ | CYCS | P99999 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7240682 | 0.95 | TERT (0.46) | TOP1TERTCYCSENPP2CYP19A1 | |
| SCHEMBL14445603 | 0.91 | TOP1 (0.62) | TOP1TERTCYCSENPP2CYP19A1 | |
| SCHEMBL29501072 | 0.85 | TERT (0.54) | TOP1TERTCYCSENPP2CYP19A1 | |
| SCHEMBL185112 | 0.85 | TERT (0.54) | TOP1TERTCYCSENPP2CYP19A1 | |
| SCHEMBL7247273 | 0.85 | CYP2A6 (0.47) | CYP19A1KDM4EALDH1A1 | |
| SCHEMBL30385992 | 0.84 | TERT (0.52) | TOP1TERTCYCSENPP2CYP19A1 | |
| SCHEMBL29021355 | 0.84 | TERT (0.52) | TOP1TERTCYCSENPP2CYP19A1 | |
| SCHEMBL21808804 | 0.84 | TERT (0.52) | TOP1TERTCYCSENPP2CYP19A1 | |
| SCHEMBL2423305 | 0.84 | TERT (0.52) | TOP1TERTCYCSENPP2CYP19A1 | |
| SCHEMBL7247327 | 0.82 | TOP1 (0.80) | TOP1TERTCYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | MYCBP, MYC, TERF2IP | TOP1 132/4885TERT 5/4885CYCS 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.