SCHEMBL185112

SCHEMBL185112

C1=Cc2nc1c(-c1cccnc1)c1ccc([nH]1)c(-c1cccnc1)c1nc(c(-c3cccnc3)c3ccc([nH]3)c2-c2cccnc2)C=C1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 4/20 0.54
▸ TOP1 P11387 2/20 0.53
▸ CYP19A1 P11511 2/20 0.49
▸ ALDH1A1 P00352 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ CYP2A6 P11509 1/20 0.47
▸ CYCS P99999 2/20 0.46
▸ ENPP2 Q13822 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ LDHA P00338 1/20 0.45
▸ EPHX2 P34913 1/20 0.45
▸ STAT3 P40763 1/20 0.44
▸ STAT1 P42224 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29501072 1.00 TERT (0.54) TERTTOP1CYP19A1ALDH1A1CYP1A2
SCHEMBL29021355 0.98 TERT (0.52) TERTTOP1CYP19A1ALDH1A1CYP1A2
SCHEMBL30385992 0.98 TERT (0.52) TERTTOP1CYP19A1ALDH1A1CYP1A2
SCHEMBL21808804 0.98 TERT (0.52) TERTTOP1CYP19A1ALDH1A1CYP1A2
SCHEMBL2423305 0.98 TERT (0.52) TERTTOP1CYP19A1ALDH1A1CYP1A2
SCHEMBL14445603 0.94 TOP1 (0.62) TERTTOP1CYP19A1ALDH1A1CYP1A2
SCHEMBL7240122 0.90 TOP1 (0.70) TERTTOP1CYP19A1CYCSENPP2
SCHEMBL7240682 0.90 TERT (0.46) TERTTOP1CYP19A1CYCSENPP2
SCHEMBL7246924 0.85 TOP1 (0.53) TERTTOP1CYP19A1ALDH1A1CYCS
SCHEMBL17366430 0.84 CYP19A1 (0.41) TERTTOP1CYP19A1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530614-B1 Porphyrin coordination polymer nanospheres and nanorods SANDIA CORPORATION (US) 2013-09-10 — — US claimed
US-8324342-B1 Porphyrin coordination polymer nanospheres and nanorods SANDIA CORPORATION (US) 2012-12-04 — — US claimed
US-7223474-B1 Heteroporphyrin nanotubes and composites SANDIA CORPORATION (US) 2007-05-29 — — US claimed
US-7132163-B1 Heteroporphyrin nanotubes and composites NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2006-11-07 — — US claimed
EP-0606453-B1 PHOTOVOLTAIC CELL ASULAB SA (CH) 1997-06-04 — — EP claimed
US-5482570-A Photovoltaic cell ASULAB S.A. (CH) 1996-01-09 — — US claimed
US-12546743-B2 Electrochemical sensor and related methods UNIVERSITY OF SOUTH FLORIDA (US) 2026-02-10 — — US disclosed
EP-3183250-B1 PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL CLAP CO LTD (KR) 2023-10-04 — — EP disclosed
US-20230296554-A1 ELECTROCHEMICAL SENSOR AND RELATED METHODS UNIVERSITY OF SOUTH FLORIDA 2023-09-21 — — US disclosed
US-11344574-B2 Fluoro substituted porphyrin compounds, pharmaceutical compositions comprising the same, and methods of preparing and using the same DUKE UNIVERSITY (US) 2022-05-31 — — US disclosed
EP-3183757-B1 ORGANIC SEMICONDUCTOR COMPOSITION COMPRISING LIQUID MEDIUM CLAP CO LTD (KR) 2022-05-04 — — EP disclosed
US-20210361702-A1 FLUORO SUBSTITUTED PORPHYRIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS OF PREPARING AND USING THE SAME DUKE UNIVERSITY 2021-11-25 — — US disclosed
EP-3687551-A1 FLUORO SUBSTITUTED PORPHYRIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS OF PREPARING AND USING THE SAME Duke University (US) 2020-08-05 — — EP disclosed
EP-1045851-A1 SUBSTITUTED PORPHYRINS DUKE UNIVERSITY (US) 2000-10-25 — — EP disclosed
WO-1999023097-A1 SUBSTITUTED PORPHYRINS DUKE UNIVERSITY (US) 1999-05-14 — — WO disclosed
EP-0606453-B1 PHOTOVOLTAIC CELL ASULAB SA (CH) 1997-06-04 — — EP disclosed
EP-0606453-A1 PHOTOVOLTAIC CELL. ASULAB SA (CH) 1994-07-20 — — EP disclosed
WO-1994003930-A1 PHOTOVOLTAIC CELL ASULAB S.A. (CH) 1994-02-17 — — WO disclosed
US-5196257-A BIDIMENSIONAL ORGANIC DIAPHRAGMS AND THEIR PREPARATION PROCESSES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1993-03-23 — — US disclosed
EP-0474533-A1 Bidimensional organic membranes and process for their preparation COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1992-03-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210361702-A1 FLUORO SUBSTITUTED PORPHYRIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS OF PREPARING AND USING THE SAME SLC46A1, CYP2B6, F12 TERT 843/4885TOP1 287/4885CYP19A1 630/4885
US-11344574-B2 Fluoro substituted porphyrin compounds, pharmaceutical compositions comprising the same, and methods of preparing and using the same SLC46A1, CYP2B6, F12 TERT 843/4885TOP1 287/4885CYP19A1 630/4885
US-12546743-B2 Electrochemical sensor and related methods EPX, MUC1, EPCAM TERT 3462/4885TOP1 4862/4885CYP19A1 3785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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