⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28609350 | 0.86 | — | — | |
| SCHEMBL18672829 | 0.76 | MEN1 (0.62) | — | |
| SCHEMBL11159092 | 0.74 | ALDH1A1 (0.60) | — | |
| SCHEMBL9012208 | 0.74 | ALDH1A1 (0.60) | — | |
| SCHEMBL4687305 | 0.74 | ALDH1A1 (0.60) | — | |
| SCHEMBL6050331 | 0.74 | ALDH1A1 (0.60) | — | |
| SCHEMBL31580839 | 0.74 | ALDH1A1 (0.54) | — | |
| SCHEMBL29061272 | 0.73 | — | — | |
| SCHEMBL10640118 | 0.72 | ALDH1A1 (0.52) | — | |
| SCHEMBL12131952 | 0.72 | ALDH1A1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875001-B1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-01-09 | — | — | EP | disclosed |
| US-9434695-B2 | Nitrogenous heterocyclic derivatives and their application in drugs | SUNSHINE LAKE PHARMA CO., LTD (CN) | 2016-09-06 | — | — | US | disclosed |
| EP-2560955-B1 | NOVEL BENZAMIDE DERIVATIVES | DONG A PHARM CO LTD (KR) | 2016-06-29 | — | — | EP | disclosed |
| CN-103570630-B | Nitrogen heterocyclic derivative and the application in medicine thereof | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2016-04-20 | — | — | CN | disclosed |
| US-9221790-B2 | Benzamide derivatives | DONG-A PHARM. CO., LTD. (KR) | 2015-12-29 | — | — | US | disclosed |
| EP-2875001-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | Sunshine Lake Pharma Co., Ltd. (CN) | 2015-05-27 | — | — | EP | disclosed |
| CN-102844301-B | Novel benzamide derivatives | DONG A PHARM CO LTD | 2015-04-22 | — | — | CN | disclosed |
| US-20150087639-A1 | Nitrogenous Heterocyclic Derivatives And Their Application In Drugs | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-03-26 | — | — | US | disclosed |
| CN-103570630-A | Heterocyclic nitrogen derivative and application thereof in medicines | GUANGDONG HEC PHARMACEUTICAL | 2014-02-12 | — | — | CN | disclosed |
| WO-2014012360-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-01-23 | — | — | WO | disclosed |
| US-20130085160-A1 | NOVEL BENZAMIDE DERIVATIVES | DONG-A PHARM. CO., LTD. (KR) | 2013-04-04 | — | — | US | disclosed |
| EP-2560955-A2 | NOVEL BENZAMIDE DERIVATIVES | Dong-A Pharm.Co., Ltd. (KR) | 2013-02-27 | — | — | EP | disclosed |
| CN-102844301-A | Novel benzamide derivatives | DONG A PHARM CO LTD | 2012-12-26 | — | — | CN | disclosed |
| WO-2011132901-A2 | NOVEL BENZAMIDE DERIVATIVES | DONG-A PHARM.CO., LTD. (KR) | 2011-10-27 | — | — | WO | disclosed |
| EP-1177187-A1 | DI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064888-A1 | DI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |
| EP-0510036-B1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE POULENC RORER SA (FR) | 1995-04-19 | — | — | EP | disclosed |
| EP-0510036-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES. | RHONE POULENC RORER SA (FR) | 1992-10-28 | — | — | EP | disclosed |
| WO-1991010662-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE-POULENC RORER S.A. (FR) | 1991-07-25 | — | — | WO | disclosed |