SCHEMBL724725

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL721506	0.92	PDE4C (0.39)	PRKAB2ABL1CSF1RLYNPRKAG1
	SCHEMBL722160	0.89	PDE4C (0.36)	PRKAB2ABL1CSF1RLYNPRKAG1
	SCHEMBL725161	0.86	PDE4C (0.42)	PDE4CALDH1A1CYP3A4SYKIKBKE
	SCHEMBL10266954	0.86	PDE4C (0.42)	PRKAB2ABL1CSF1RLYNPRKAG1
	SCHEMBL722258	0.83	JAK2 (0.39)	PDE4CALDH1A1CYP3A4IKBKETBK1
	SCHEMBL723668	0.83	PGK1 (0.41)	PDE4CPTGESALOX5
	SCHEMBL722228	0.81	PDE4C (0.43)	PDE4CTGFBR2SYKFYNCYP1A1
	SCHEMBL723546	0.81	JAK2 (0.44)	PRKAB2CSF1RPRKAG1PRKAA1PDE4C
	SCHEMBL723093	0.79	PDE4C (0.55)	PDE4CALDH1A1CYP3A4SYKFYN
	SCHEMBL15210341	0.77	CSF1R (0.45)	PRKAB2ABL1CSF1RLYNPRKAG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.