Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424040 | 0.93 | MAOA (0.65) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL3647660 | 0.92 | CHRM2 (0.66) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL9182514 | 0.85 | MAOA (0.56) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL17560742 | 0.83 | CHRM2 (0.59) | CHRM2TDP1SIGMAR1DPP7 | |
| Hydrochloric Acid SCHEMBL9195735 | 0.83 | MAOA (0.55) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL8625123 | 0.82 | MAOA (0.58) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL8624899 | 0.82 | MAOA (0.58) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL4303544 | 0.81 | EPHX1 (0.73) | MAOAEPHX1SIGMAR1ANPEP | |
| SCHEMBL20466361 | 0.81 | EPHX1 (0.73) | MAOAEPHX1SIGMAR1ANPEP | |
| SCHEMBL4302698 | 0.81 | EPHX1 (0.73) | MAOAEPHX1SIGMAR1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030045755-A1 | Polyamine analogues as cytotoxic agents | MEDIQUEST THERAPEUTICS, INC. | 2003-03-06 | — | — | US | disclosed |