Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 4/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 3/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | CYCS | P99999 | 3/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | HCK | P08631 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | SIK1 | P57059 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252275 | 0.82 | TOP1 (0.55) | MMP9MMP2MMP8MMP13TOP1 | |
| SCHEMBL16080128 | 0.73 | TOP1 (0.52) | MMP9MMP2MMP8MMP13TOP1 | |
| SCHEMBL7247633 | 0.72 | DNMT1 (0.50) | MMP9MMP2MMP8MMP13DNMT1 | |
| Hydrochloric Acid SCHEMBL7245380 | 0.71 | TOP1 (0.44) | MMP9MMP2MMP8MMP13TOP1 | |
| Hydrochloric Acid SCHEMBL7248738 | 0.70 | TOP1 (0.43) | MMP9MMP2MMP8MMP13TOP1 | |
| SCHEMBL12846657 | 0.70 | AURKA (0.73) | AURKAMAPK13CHEK2NTRK1RET | |
| SCHEMBL15131997 | 0.70 | TOP1 (0.66) | TOP1CYCSCHEK2 | |
| SCHEMBL2403632 | 0.69 | TOP1 (0.54) | TOP1CYCSAURKAITK | |
| SCHEMBL16923748 | 0.69 | ALDH1A1 (0.55) | TOP1CYCS | |
| SCHEMBL16912677 | 0.69 | TOP1 (0.54) | TOP1CYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | MYCBP, MYC, TERF2IP | MMP9 4147/4885MMP2 3169/4885MMP8 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.