SCHEMBL724774

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL721887	0.89	ALDH1A1 (0.50)	CYP3A4CYP2D6CYP2C19KDM4ETP53
	SCHEMBL722067	0.86	CYP3A4 (0.56)	CYP3A4CYP2D6CYP2C19KDM4ETP53
	SCHEMBL723786	0.85	CYP3A4 (0.48)	CYP3A4CYP2D6CYP2C19KDM4ETP53
	SCHEMBL723378	0.83	CYP3A4 (0.47)	CYP3A4CYP2D6CYP2C19KDM4ETP53
	SCHEMBL721613	0.83	VSIR (0.43)	CYP3A4CYP2D6CYP2C19KDM4ETP53
	SCHEMBL723264	0.83	PLCG1 (0.51)	EGFR
	SCHEMBL723570	0.81	CYP3A4 (0.46)	CYP3A4CYP2D6CYP2C19KDM4ETP53
	SCHEMBL721399	0.77	NEK1 (0.48)	CYP3A4KDM4ENPC1RAB9ASMN1; SMN2
	SCHEMBL723076	0.77	SCN9A (0.44)	USP2HSD17B10NPC1SMN1; SMN2MAPT
	SCHEMBL724014	0.76	NPC1 (0.47)	KDM4EMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.